Polynucleotide Skin Treatment (Salmon Sperm Facial) in Bangalore

No — the name is marketing shorthand that stuck. What is injected is polynucleotides (PDRN): purified fragments of DNA derived from salmon, processed to remove proteins and other biological material. Nothing about the treatment involves sperm, and the substance in the syringe is a highly purified pharmaceutical-grade product.

A filler is a gel placed under the skin to add volume or contour — it changes shape. Polynucleotides add no volume at all. They are placed into the skin to signal repair, so the improvement is in skin quality: hydration, elasticity, texture and fine lines, with your features left exactly as they are.

Skin boosters and Profhilo are hyaluronic acid — they hydrate by holding water within the skin. Polynucleotides work through a different mechanism: the DNA fragments prompt the skin's own repair and collagen response rather than supplying hydration directly. Which suits you better depends on whether your main issue is dryness or overall skin quality and repair — the consultation settles that.

Polynucleotide products are highly purified, and reactions are uncommon — but it is derived from salmon, so tell your doctor about any fish allergy, along with any other allergies and your medical history. The consultation screens for this specifically, and as with any injection there are expected short-lived effects like bumps, redness and possible bruising at the injection points.

A course is typically 2–4 sessions spaced 2–4 weeks apart, and results build gradually over the weeks after each session rather than appearing overnight — the effect comes from your skin's own response, which takes time. Worth knowing upfront: this is a newer treatment and the evidence base is still building. Early studies and clinical experience are encouraging for hydration, elasticity and fine lines, but long-term comparative data is more limited than for older treatments, and we would rather say that plainly than oversell it.

Treatment is deferred or declined with a known fish or product allergy, active skin infection or open wounds in the area, certain skin conditions, and during pregnancy or breastfeeding. If your main concern is volume loss, sagging or deep folds, this is also the wrong tool — a different treatment plan would serve you better, and the doctor will say so at the consultation.

Numbing cream is applied first, and most patients describe brief stinging at each injection point rather than sustained pain. The under-eye area is more sensitive than the cheeks, which is part of why the numbing time is not skipped.

Polynucleotide skin treatments became widely known through Korean aesthetic clinics, where they have been popular for several years, and the "salmon DNA" framing travelled with them through skincare content. The treatment itself is now available well beyond Korea — what matters is that it is administered by a doctor who has assessed your skin.