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Patient question · Indiranagar & Bellandur

Is the salmon sperm facial safe?

Reviewed by The Aesthetic Edge medical team

Polynucleotide products are highly purified and reactions are uncommon. The one disclosure that genuinely matters is a **fish allergy**, because the material is derived from salmon — tell your doctor. And despite the name, nothing about the treatment involves sperm: what is injected is purified DNA fragments, processed to remove proteins and other biological material.

First, the name

Nothing about the treatment involves sperm. The name is marketing shorthand that stuck, and it is the single biggest barrier to people evaluating this treatment sensibly.

What is injected is polynucleotides (PDRN) — purified fragments of DNA derived from salmon, processed to remove proteins and other biological material. The substance in the syringe is a highly purified pharmaceutical-grade product.

The safety position

Polynucleotide products are highly purified, and reactions are uncommon.

The disclosure that matters: it is derived from salmon, so tell your doctor about any fish allergy. That is the specific, non-obvious thing this treatment requires you to mention, and it is easy to forget precisely because the treatment is discussed as a facial rather than as an injectable.

What it is, clinically

The product used here is Rejuran, the Korean-developed PDRN line. It comes in a few different formulations for different areas of concern — skin, under-eye, scalp — and your doctor confirms which fits your concern at consultation rather than defaulting to one for everybody.

What it does not do

Polynucleotides add no volume at all. They are placed into the skin to signal repair, so the improvement is in skin quality — hydration, elasticity, texture and fine lines — with your features left exactly as they are.

This distinguishes it from a filler, which changes shape. It also works differently from hyaluronic acid skin boosters and Profhilo, which hydrate by holding water within the skin.

Recognised effects

  • Injection-point bumps and redness.
  • Bruising.
  • Tenderness or mild swelling.
  • Rare reactions, discussed at consultation.

What to raise at consultation

Any fish allergy, your full medical history and medication, and which Rejuran formulation is being proposed for your concern and why. That last question is worth asking specifically, since the line has several.

Full detail on the Rejuran / polynucleotide page; see also how many sessions are needed. Consultation ₹500, waived against treatment.

The treatment pageRejuran (Polynucleotide) Skin Treatment — Salmon Sperm Facial

Rejuran (PDRN) skin treatment in Bangalore — the polynucleotide "salmon sperm facial". Purified salmon DNA micro-injected for skin repair, doctor-administered.

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Related questions

In short

Is the salmon sperm facial safe?
Polynucleotide products are highly purified and reactions are uncommon. The one disclosure that genuinely matters is a **fish allergy**, because the material is derived from salmon — tell your doctor. And despite the name, nothing about the treatment involves sperm: what is injected is purified DNA fragments, processed to remove proteins and other biological material.

Related at The Aesthetic Edge

Get a doctor's read before you decide anything

₹500 consultation, waived off against your treatment. Indiranagar or Bellandur — closed Wednesdays.

Reviewed by The Aesthetic Edge medical team. General information, not medical advice — your treatment is decided at an in-person consultation. Terms & Conditions