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skin · Updated 15 February 2026

Planning Rejuran (Salmon Sperm Facial) Before Your Wedding: The Bride's Runway

By The Aesthetic Edge Editorial TeamReviewed by The Aesthetic Edge medical team
A facial micro-injection session being administered by a doctor at The Aesthetic Edge

Rejuran is a months-out plan, not a fortnight-out one. A course is typically two to four sessions spaced two to four weeks apart, and the result builds gradually over the weeks after each session rather than arriving at the end of it. Count backwards from your first function, allow for the full course plus settling time, and start early.

Brides very often find this treatment late, when the wedding is close and the skin they wanted has not turned up. The honest answer at that point is sometimes that the timing has gone, and a clinic willing to say so is doing you a favour.

How far ahead should I actually start?

Plan on months. Take the longest version of the documented course — four sessions at four-week spacing — and that alone is roughly twelve weeks from your first appointment to your last. Then add time after the final session for the response to build, because that is where the visible improvement comes from.

Put those together and starting four to five months before your first function gives you room to complete a full course, absorb a rescheduled session if something comes up, and let the last one settle without watching the calendar. Starting earlier than that is not wasted; starting much later is where the compromises begin.

Count backwards from the first function, not the wedding day

This is the part people get wrong. A wedding here is rarely a single afternoon. If your mehendi is on the Thursday and the reception is the following Sunday, the date that matters for planning is the Thursday — and often the engagement shoot or the pre-wedding photographs before that.

Write down the first event you will be photographed at, and treat that as the deadline. Everything below counts back from there.

What does the runway look like, month by month?

Roughly, and subject to what the doctor plans for your skin at the consultation:

  • Five months out: consultation. This is where the doctor examines your skin, confirms polynucleotides suit the concern, screens for allergies and the conditions that rule injecting out, and tells you honestly whether the runway you have is workable.
  • Four months out: first session. Injection-point bumps and redness settle in 24 to 48 hours; bruising, if any, typically clears within a few days.
  • Three to two months out: remaining sessions, spaced two to four weeks apart, each one reviewed before it goes ahead.
  • The last month: nothing new. Let the response finish building and let the skin be left alone.

That final line is doing more work than it looks. The improvement from this treatment is produced by your own skin over weeks, so the month before the wedding is when it pays off — not when you start.

What if my wedding is six weeks away?

Then say so at the consultation and let the doctor tell you what is sensible, rather than deciding in advance that you will squeeze a course in. A short runway is not automatically a no, but it does change the conversation: fewer sessions completed means less of the cumulative effect, and there is no way to speed up the skin's own response.

What we will not do is compress the spacing to make the arithmetic work.

Can the sessions be moved closer together to fit?

No, and the reason is not administrative. The two-to-four-week gap exists so each session lands on skin that has already begun responding to the last one, and so the doctor can see what your skin actually did before deciding what to do next. Sessions are reviewed at each visit for exactly that reason. Collapsing the gaps removes the review and removes the sequence the course depends on.

If the calendar and the course genuinely do not fit, the better answer is a different plan — which might be fewer sessions with realistic expectations, or a different treatment altogether.

What should I not attempt close to the date?

Three things, plainly.

A first-ever session of anything injectable in the final weeks. You do not yet know how your own skin reacts. Bumps and redness usually settle in 24 to 48 hours and bruising usually clears within days — but "usually" is not a promise, and the week of your wedding is a poor time to find out you bruise more than average. If you take any blood-thinning medication, bruising is more likely, which is one of several reasons your medication list matters.

Stacking new treatments together. Adding a facial, a peel, a new prescription cream and an injectable in the same fortnight makes it impossible to know what caused what, and gives your skin several things to settle from at once. Sequencing is a consultation decision — bring your whole bridal plan, including anything a salon has suggested, and let the doctor order it.

Anything on a face with an active problem. Treatment is deferred with active skin infection or open wounds in the treated area, along with certain skin conditions, a known fish or product allergy — Rejuran is derived from salmon — and during pregnancy or breastfeeding. A deferral close to the date is disruptive, which is another argument for the early consultation.

Will this fix everything I want fixed?

No, and it is worth being clear about what it does not do. Polynucleotides add no volume and change nothing about your face shape. Nothing is placed to plump, lift or contour, so if what is troubling you in photographs is volume loss, sagging or deep folds, this is the wrong tool and a doctor should say so.

What it addresses is skin quality — hydration, elasticity, texture, fine lines, and the thin crepey skin under the eyes that concealer settles into. That last one is a common bridal concern and one of the areas this treatment is most often chosen for, precisely because the aim is skin quality rather than volume in a place where volume easily looks wrong.

One caveat we would rather give you now than after you have paid: this is a newer treatment and the evidence base is still building. Early studies and clinical experience are encouraging, but an outcome cannot be promised — and on a wedding runway, expectations are as much a part of the plan as the sessions are.

What should make me ring the clinic between sessions?

Injection-point bumps, redness, mild swelling and bruising that are settling day by day are expected. Ring promptly, rather than waiting for the next session, if you notice increasing pain, heat, redness spreading rather than fading, or any reaction you did not expect. Please do not sit at home deciding for yourself whether it is serious — with a wedding coming there is a real temptation to hope something settles, and that is the temptation to resist. If something is worsening quickly and you cannot reach us out of hours, seek medical care locally rather than waiting for the clinic to open.

Where to start

If your main complaint is dryness rather than tired-looking skin, skin boosters and Profhilo are hyaluronic acid treatments that hold water in the skin — a different mechanism worth putting side by side with this one at your consultation.

The consultation is ₹500, waived off against treatment. Bring your wedding dates, all of them. Book an appointment as early in your planning as you can bear to, because the one thing no clinic can give you back is time.

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General information, not medical advice — your treatment is decided at an in-person consultation. Terms & Conditions