How to Prepare for a Salmon Sperm Facial (Rejuran), and What to Avoid Beforehand

Preparation for the salmon sperm facial is mostly disclosure, not restriction. Tell the clinic about any fish allergy and every medication you take — blood thinners especially, because they make bruising more likely. Do not stop a prescribed medicine on your own. Then plan around 24 to 48 hours of small bumps and redness, and allow time for numbing cream on the day.

Most of the preparation people worry about is the wrong preparation. Here is what actually changes how your session goes.

Does the consultation count as preparation?

It is the preparation. The consultation is where a doctor examines your skin, confirms polynucleotides suit what is actually bothering you, and screens for the allergies and conditions that would rule injecting out — and it happens before anything touches your skin, not on the same conveyor belt as the treatment.

It is also the point at which the plan is decided: which Rejuran formulation fits your concern, which areas are treated, and how many sessions. Rejuran is a product line rather than a single syringe, and the formulations differ by area of concern. Which one you get is confirmed by your doctor at the consultation, not defaulted to one for everybody, so nobody can tell you in advance which it will be — including us.

The consultation is ₹500, waived against your treatment.

What do you need to disclose, and how early?

At the consultation, and again on the day if anything has changed. Specifically:

• Any fish allergy. The product is derived from salmon. This is screened for, but say it out loud rather than assuming a form covers it.
• Every medication and supplement you take. Blood-thinning medication matters most, because bruising is more likely on it.
• Pregnancy or breastfeeding. Treatment is deferred.
• Any other allergies and your medical history, in full.
• Any active skin infection, broken skin or open wounds in the area you want treated.
• Any skin condition you are being treated for, and what you are using on it.

None of this is a formality. Allergies and the conditions that make injecting inadvisable are the things the screen is looking for, and an omission there is the one preparation mistake with real consequences.

Should you stop any medication beforehand?

Not on your own, and not because an article told you to. If you take blood-thinning medication, the honest position is that bruising is more likely — that is a reason to tell your doctor, so the risk is factored into the plan and into your expectations, and not a reason to skip a dose.

Stopping a prescribed medicine to avoid a bruise is trading a real medical risk for a cosmetic one. Tell the clinic what you take, and let the doctor who prescribed it and the doctor treating you make that call between them.

What about your skincare routine in the week before?

Tell the clinic what you use and ask specifically. There is no blanket pre-treatment skincare protocol attached to this treatment in the way there is for a peel, so we are not going to invent a countdown of days to stop things — but strong actives, recent procedures and anything you are using on a prescription are all worth raising at the consultation, and the answer may differ for the under-eye area than for the cheeks.

What is straightforwardly sensible: arrive with clean skin and, if you can, without makeup on the area being treated. The skin is cleansed at the clinic anyway, so this saves time rather than changing the outcome.

What actually happens on the day, and how long does it take?

Longer than the injecting itself, which is the part people misjudge. The skin is cleansed, numbing cream is applied and then left to work — that waiting time is deliberate and is not skipped, particularly around the eyes, which are more sensitive than the cheeks. Only then does the injecting begin.

The treatment itself is a series of small, shallow injections placed across the area with fine needles, at a depth chosen for your concern. Most people describe brief stinging at each point rather than sustained pain. Book it as a proper appointment rather than something you can squeeze into a lunch break, and ask the clinic for a realistic duration when you book so you are not clock-watching.

When should you book it around work, an event or a wedding?

Work backwards from 24 to 48 hours. Small raised bumps and redness where the needle entered are expected, and they usually settle within a day or two as the product disperses. Bruising is possible at any injection point and typically clears within a few days. Tenderness or mild swelling in the first day or two is common, especially around the eyes.

So: a Friday session gives you a weekend. A session the day before a wedding does not give you anything, and no amount of planning shortens the settling time.

There is a bigger scheduling point that people miss entirely. This is a course — typically two to four sessions, spaced two to four weeks apart — and the results build gradually over the weeks after each session as your skin's own repair response gets going, rather than appearing on the drive home. If you have an occasion in mind, the calendar you need to map is the whole course, not one appointment. Talk about the date at the consultation and let the plan be built around it.

What should you bring with you?

A list of your medications rather than a memory of them, your allergy history, and your questions written down — because the ones you meant to ask are the ones that vanish once you are in the chair.

Two worth having on the list: what this treatment is not going to do for you, and what the alternative would be. Polynucleotides add no volume and change nothing about your face shape. If your main concern turns out to be volume loss, sagging or deep folds, this is the wrong tool, and a different plan would serve you better — you should expect to be told that plainly.

How is this different from preparing for skin boosters or Profhilo?

Practically, less than you would think; mechanically, quite a lot. Skin boosters and Profhilo are hyaluronic acid and hydrate by holding water within the skin. Polynucleotides prompt your own repair and collagen response instead of supplying hydration directly.

If you are weighing one against the other, that is a consultation question rather than a preparation question — and the honest answer depends on whether your real problem is dryness or overall skin quality.

What should you watch for afterwards, and when do you ring?

Expect the bumps and redness to settle within 24 to 48 hours, and any bruising within a few days. That is the normal picture.

Please do not sit at home working out whether something is normal. Allergic reactions and infection are uncommon but possible with any injectable. Contact the clinic promptly, rather than waiting for your next scheduled session, if you have increasing pain, heat or spreading redness, if swelling worsens instead of settling, or if anything at all is unexpected or does not match what you were told to expect. None of that is common, and none of it is yours to assess on your own — ring the branch that treated you, and ask to be seen if you are unsure.

One thing to know before you commit

This is a newer treatment and the evidence base is still building. Early studies and clinical experience are encouraging for hydration, elasticity and fine lines, but long-term comparative data is more limited than for older treatments. That is worth hearing before you book rather than after.

Cost depends on the area treated and how many sessions your skin needs, so there is no single figure to quote — you will have it in writing before anything starts.

Ready to have your skin looked at properly? Book an appointment and bring your list.